CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Congenic Iddm1 and Iddm2 homozygous WOKW.BB rats do not develop diabetes, but their (WOKW.4BB x BB/OK)F1 hybrids
DOI 10.1055/s-2007-982301
Bibliografische Angaben
Nachweis in CareLit
Autor:innenN Klöting, B Wilke, B Kuttler, I Klöting
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe08/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aim: WOKW rats develop facets of the metabolic syndrome and BB rats develop type 1 diabetes. Both strains are common the RT1u haplotype of major histocompatibility complex (MHC) which is essential for type 1 diabetes development in the BB rat termed Iddm1. However, BB rats need an additional gene to develop type 1 diabetes termed Iddm2 and identified as immune-associated nucleotide 4 (Ian4 or Gimap5). Because WOKW l…
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Zitierempfehlung
N Klöting, B Wilke, B Kuttler, I Klöting (2007) Congenic Iddm1 and Iddm2 homozygous WOKW.BB rats do not develop diabetes, but their (WOKW.4BB x BB/OK)F1 hybrids. Diabetologie und Stoffwechsel (08). https://doi.org/10.1055/s-2007-982301
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