CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Insulin-independent GLUT4 accumulation at cell surface in AP-1 knockdown 3T3-L1 adipocytes
DOI 10.1055/s-2007-982335
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Autor:innenU Schmidt, HG Joost, H Al-Hasani
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe08/2007
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background and aims: Stimulation by insulin results in a rapid and reversible translocation of GLUT4 from storage vesicels to the plasma membrane in muscle and adipose tissue. A N-terminal phenylalanine-containing amino acid motif (F5QQI) is required for the endocytosis and subsequent sorting of GLUT4 into the vesicles. The F5A-mutant of GLUT4 accumulates at the cell-surface in an insulin-independent manner. In prev…
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Zitierempfehlung
U Schmidt, HG Joost, H Al-Hasani (2007) Insulin-independent GLUT4 accumulation at cell surface in AP-1 knockdown 3T3-L1 adipocytes. Diabetologie und Stoffwechsel (08). https://doi.org/10.1055/s-2007-982335
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