CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Drug-induced desensitization of insulin secretion
DOI 10.1055/s-2007-982336
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Nachweis in CareLit
Autor:innenK Hatlapatka, A Wienbergen, A Jörns, I Rustenbeck
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe08/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Desensitization of insulin secretion is a reversible state of decreased secretory responsiveness of the endocrine pancreas after prolonged exposure to nutrient or non-nutrient stimuli. The underlying mechanisms are poorly understood inspite of their obvious relevance. Methods: Mouse islets were cultured for 20h in RPMI medium containing tolbutamide or the imidazoline efaroxan. Secretion was measured by…
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Zitierempfehlung
K Hatlapatka, A Wienbergen, A Jörns, I Rustenbeck (2007) Drug-induced desensitization of insulin secretion. Diabetologie und Stoffwechsel (08). https://doi.org/10.1055/s-2007-982336
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