CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Insulin prolongs lifespan and preserves neuronal function under hyperglycemic conditions in C. elegans
DOI 10.1055/s-2007-982385
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Autor:innenY Ibrahim, A Schlotterer, G Kukudov, P Humpert, A Hamann, J Tafel, A Bierhaus, PP Nawroth, M Morcos
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe08/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: In the nematode Caenorhabditis elegans (C. elegans), the insulin receptor and insulin signal transduction system is highly homologous to the human system and is involved in antioxidative defense and determination of lifespan. Hyperglycemic culture conditions lead to neuronal dysfunction and reduction of lifespan in C. elegans. Aim of this study was to investigate the effects of normal human insulin (Actrapid®)…
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Zitierempfehlung
Y Ibrahim, A Schlotterer, G Kukudov, P Humpert, A Hamann, J Tafel, A Bierhaus, PP Nawroth, M Morcos (2007) Insulin prolongs lifespan and preserves neuronal function under hyperglycemic conditions in C. elegans. Diabetologie und Stoffwechsel (08). https://doi.org/10.1055/s-2007-982385
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