CareLit · DOI-Nachweis · Geburtshilfe und Frauenheilkunde
Apoptotic effects of signal transduction inhibitors on human tumor cells with different PTEN expression
DOI 10.1055/s-2007-983524
Bibliografische Angaben
Nachweis in CareLit
Autor:innenG Pfeiler, C Lattrich, O Treeck, O Ortmann
ZeitschriftGeburtshilfe und Frauenheilkunde
Ausgabe06/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
1. Introduction: An important mechanism of antitumoral targeted therapies is the induction of apoptosis in tumor cells. Tamoxifen and trastuzumab (Herceptin), respectively, are able to trigger apoptosis in human breast cancer cells. But, frequently altered apoptotic signal cascades, for instance through PTEN mutations, help tumor cells to escape antitumoral therapy. We intended to study to which extent the apoptotic…
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Zitierempfehlung
G Pfeiler, C Lattrich, O Treeck, O Ortmann (2007) Apoptotic effects of signal transduction inhibitors on human tumor cells with different PTEN expression. Geburtshilfe und Frauenheilkunde (06). https://doi.org/10.1055/s-2007-983524
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