CareLit · DOI-Nachweis · Aktuelle Neurologie
Autosomal dominantly inherited Parkinson's disease: first investigation of the brain of a patient with the A30P mutation in the alpha-synuclein gene and initial insights into the degenerative process
DOI 10.1055/s-2007-987447
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Nachweis in CareLit
Autor:innenR Krüger, K Seidel, L Schöls, K Del Tredici, K Gierga, O Rieß, S Frank, W Scherzed, A Rami, C Müller, I Bechmann, T Deller, U Rüb
ZeitschriftAktuelle Neurologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
To date, three point mutations in the alpha-synuclein (SNCA) gene (Ala30Pro, Glu46Lys, and Ala53Thr) have been identified in families with autosomal dominantly inherited Parkinson's disease (PD). Carriers of the Ala30Pro mutation in the SNCA gene display typical clinical signs of idiopathic Parkinson's disease (IPD), including a positive and sustained response to levodopa therapy. The observation that SNCA represent…
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Zitierempfehlung
R Krüger, K Seidel, L Schöls, K Del Tredici, K Gierga, O Rieß, S Frank, W Scherzed, A Rami, C Müller, I Bechmann, T Deller, U Rüb (2007) Autosomal dominantly inherited Parkinson's disease: first investigation of the brain of a patient with the A30P mutation in the alpha-synuclein gene and initial insights into the degenerative process. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2007-987447
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