CareLit · DOI-Nachweis · Aktuelle Neurologie
Brain endothelial PPAR-gamma controls inflammation-induced CD4+ T cell adhesion and transmigration in vitro
DOI 10.1055/s-2007-987505
Bibliografische Angaben
Nachweis in CareLit
Autor:innenL Klotz, L Diehl, I Dani, H Neumann, E Endl, T Klockgether, B Engelhardt, P Knolle
ZeitschriftAktuelle Neurologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
An important step in the pathogenesis of multiple sclerosis is the adhesion and subsequent transmigration of activated encephalitogenic CD4+ T cells across highly specialized endothelial cells (EC) participating in the formation of the blood-brain-barrier. Recruitment of CD4+ T cells across brain EC relies on interaction with EC-expressed adhesion molecules that allow immune surveillance of the CNS, but also promote…
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Zitierempfehlung
L Klotz, L Diehl, I Dani, H Neumann, E Endl, T Klockgether, B Engelhardt, P Knolle (2007) Brain endothelial PPAR-gamma controls inflammation-induced CD4+ T cell adhesion and transmigration in vitro. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2007-987505
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