CareLit · DOI-Nachweis · Aktuelle Neurologie
Treatment of RRMS patients with the PPARgamma agonist actos: results of a phase I trial
DOI 10.1055/s-2007-987507
Bibliografische Angaben
Nachweis in CareLit
Autor:innenC Kaiser, D Shukla, G Stebbins, D Skias, G Katsamakis, D Stefoski, D Jeffrey, D Feinstein
ZeitschriftAktuelle Neurologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Previous studies have shown that an agonist of the peroxisome proliferator activated receptor gamma (PPARg) that is currently used to treat type 2 diabetes, also shows anti-inflammatory effects in T-cells and glial cells; improves glial metabolism; and is neuroprotective. In mouse models of multiple sclerosis, PPARg agonists were shown to reduce disease severity, and in a case report the agonist Actos (pioglitazone)…
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Zitierempfehlung
C Kaiser, D Shukla, G Stebbins, D Skias, G Katsamakis, D Stefoski, D Jeffrey, D Feinstein (2007) Treatment of RRMS patients with the PPARgamma agonist actos: results of a phase I trial. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2007-987507
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