CareLit · DOI-Nachweis · Aktuelle Neurologie
Preclinical and clinical applications of enzastaurin in the treatment of malignant gliomas
DOI 10.1055/s-2007-987516
Bibliografische Angaben
Nachweis in CareLit
Autor:innenG Tabatabai, M Weller, M Bamberg, M Tatagiba, W Wick
ZeitschriftAktuelle Neurologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Radiotherapy is essential in the treatment of malignant gliomas. However, it enhances the invasion of glioma cells and the secretion of vascular endothelial growth factor (VEGF) in experimental gliomas. We therefore assessed the combined effects of the protein kinase C inhibitor enzastaurin and radiotherapy in vitro and in vivo. The combination of enzastaurin and irradiation enhanced apoptosis in glioma cells in vit…
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Zitierempfehlung
G Tabatabai, M Weller, M Bamberg, M Tatagiba, W Wick (2007) Preclinical and clinical applications of enzastaurin in the treatment of malignant gliomas. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2007-987516
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