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The inflammatory response in experimental autoimmune encephalomyelitis is redirected from the spinal cord to the cerebellum in transgenic mice with astrocyte production of IL-6

M Müller, A Quintana, D Getts, E Sanz, MJ Hofer, EB Ringelstein, NJC King, J Hidalgo, IL Campbell · Aktuelle Neurologie · Ausgabe 09/2007

DOI 10.1055/s-2007-987605

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Autor:innenM Müller, A Quintana, D Getts, E Sanz, MJ Hofer, EB Ringelstein, NJC King, J Hidalgo, IL Campbell
ZeitschriftAktuelle Neurologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Interleukin (IL)-6 is essential for the induction of experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis. Recent studies further demonstrated that IL-6 is involved in the generation of Th17 T-cells, which mediate the tissue damage during EAE. To further clarify the role of IL-6 in EAE, we examined transgenic mice with astrocyte and predominantly cerebellar but not spinal cord prod…

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Zitierempfehlung

M Müller, A Quintana, D Getts, E Sanz, MJ Hofer, EB Ringelstein, NJC King, J Hidalgo, IL Campbell (2007) The inflammatory response in experimental autoimmune encephalomyelitis is redirected from the spinal cord to the cerebellum in transgenic mice with astrocyte production of IL-6. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2007-987605

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