CareLit · DOI-Nachweis · Aktuelle Neurologie
Induction of prostaglandin E2 receptor 3 (EP3) in SK-N-SH-cells by IL-1 beta: involvement of p38-MAPK and NFkappaB
DOI 10.1055/s-2007-987628
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Gräf, E Candelario-Jalil, M Hüll, B Fiebich
ZeitschriftAktuelle Neurologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
IL-1beta and PGE2 are found to be increased in several neuro-inflammatory and degenerative processes in the brain, such as cerebral ischemia (CI), traumatic brain injuries or Alzeimer's disease (AD). PGE2 exerts its several effects by binding to four different G-protein-coupled receptors named EP1-EP4. Stimulation with the pro-inflammatory cytokine IL-1beta produces a marked up-regulation of EP3 synthesis in the hum…
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Zitierempfehlung
S Gräf, E Candelario-Jalil, M Hüll, B Fiebich (2007) Induction of prostaglandin E2 receptor 3 (EP3) in SK-N-SH-cells by IL-1 beta: involvement of p38-MAPK and NFkappaB. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2007-987628
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