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Modulation of the calcium-activated BK-channel of the inner mitochondrial membrane by hypoxia

D Siemen, Y Cheng, X Gu, P Bednarczyk, GG Haddad, FR Wiedemann, CW Wallesch · Aktuelle Neurologie · Ausgabe 09/2007

DOI 10.1055/s-2007-987642

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Autor:innenD Siemen, Y Cheng, X Gu, P Bednarczyk, GG Haddad, FR Wiedemann, CW Wallesch
ZeitschriftAktuelle Neurologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

It is known from stroke that hypoxia has dramatic effects on neuronal energy metabolism and on cell survival. It was unknown, however, whether the mitochondrial ion channels are susceptible to hypoxia though they are involved in ischemic preconditioning and in the intrinsic cascade of apoptotic cell death. Therefore, we studied the effect of hypoxia on several parameters of the current through the Ca2+ -activated po…

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D Siemen, Y Cheng, X Gu, P Bednarczyk, GG Haddad, FR Wiedemann, CW Wallesch (2007) Modulation of the calcium-activated BK-channel of the inner mitochondrial membrane by hypoxia. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2007-987642

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