CareLit · DOI-Nachweis · Aktuelle Neurologie
Circadian alterations of dentate gyrus excitability may contribute to the afternoon peak of seizures in experimental mesial temporal lobe epilepsy
DOI 10.1055/s-2007-987721
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Autor:innenJ Matzen, K Buchheim, M Holtkamp
ZeitschriftAktuelle Neurologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
In human mesial temporal lobe epilepsy (mTLE), seizure occurrence peaks in the late afternoon and early evening. This temporal binding of seizures is also manifest in animal models of mTLE developing as a consequence of electrically-induced status epilepticus. In this study, we hypothesized that circadian alterations in excitatory and inhibitory functions of the dentate gyrus (DG), which is believed to regulate the…
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Zitierempfehlung
J Matzen, K Buchheim, M Holtkamp (2007) Circadian alterations of dentate gyrus excitability may contribute to the afternoon peak of seizures in experimental mesial temporal lobe epilepsy. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2007-987721
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