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RNA expression signatures in peripheral blood cells of interferon-beta 1a (IM) treated MS patients disclose differentially expressed genes of therapy predicting value

D Koczan, R Goertsches, P Serrano-Fernandez, HJ Thiesen, S Möller, UK Zettl · Aktuelle Neurologie · Ausgabe 09/2007

DOI 10.1055/s-2007-987764

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Autor:innenD Koczan, R Goertsches, P Serrano-Fernandez, HJ Thiesen, S Möller, UK Zettl
ZeitschriftAktuelle Neurologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Objective: This longitudinal systematic gene expression study focused on the disease multiple sclerosis (MS) and the effects of medication by interferon-beta-1a (IFNß1a). It was the aim to detect surrogate markers for therapeutic intervention (discern RNA-profiles derived from (non-)responders to treatment) in human PBMCs and to infer accessory regulatory pathways of applied MS drug. Background: interferon-beta (IFN…

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D Koczan, R Goertsches, P Serrano-Fernandez, HJ Thiesen, S Möller, UK Zettl (2007) RNA expression signatures in peripheral blood cells of interferon-beta 1a (IM) treated MS patients disclose differentially expressed genes of therapy predicting value. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2007-987764

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