CareLit · DOI-Nachweis · Aktuelle Neurologie
The role of ER stress for the pathogenesis of SCA3 in primary cell culture experiment
DOI 10.1055/s-2007-987775
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Autor:innenC Funke, J Hübener, H Wolburg, T Schmidt, H Toresson, O Rieß
ZeitschriftAktuelle Neurologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
The spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease, is an autosomal dominantly inherited neurodegenerative disorder, which is caused by an expanded CAG repeat in the ataxin-3 gene. After a decade of research the function of ataxin-3 is still unidentified. Here we investigated, whether there is a causal relationship between the pathogenesis of SCA3 and endoplasmic reticulum (ER) stress. Th…
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Zitierempfehlung
C Funke, J Hübener, H Wolburg, T Schmidt, H Toresson, O Rieß (2007) The role of ER stress for the pathogenesis of SCA3 in primary cell culture experiment. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2007-987775
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