CareLit · DOI-Nachweis · Aktuelle Neurologie
Physical activity fails to rescue impaired hippocampal neurogenesis in R6/2 mice model of Huntington's disease
DOI 10.1055/s-2007-987799
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Mahesh, Z Kohl, B Winner, R Aigner, C Gross, S Couillard-Despres, U Bogdahn, L Aigner, J Winkler
ZeitschriftAktuelle Neurologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Huntington's disease (HD) is a dominantly inherited disorder characterized by hyperkinesia, cognitive deficits and psychiatric symptoms. HD is caused by an expanded CAG-triplet nucleotide repeat stretch on HD gene that encodes for an extended poly-glutamine tract in the huntingtin protein, resulting in intracellular aggregate formation and neurodegeneration. Adult stem cells are considered as potential therapeutic s…
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Zitierempfehlung
K Mahesh, Z Kohl, B Winner, R Aigner, C Gross, S Couillard-Despres, U Bogdahn, L Aigner, J Winkler (2007) Physical activity fails to rescue impaired hippocampal neurogenesis in R6/2 mice model of Huntington's disease. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2007-987799
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