CareLit · DOI-Nachweis · Aktuelle Neurologie
Induction of fibril-like beta-amyloid aggregates by a natural substance decreases soluble oligomers and protects from neurotoxicity
DOI 10.1055/s-2007-987948
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Nachweis in CareLit
Autor:innenM Herbst, J Bieschke, Q Wang, R Lurz, A Boeddrich, A Otto, R Anwyl, DM Walsh, EE Wanker
ZeitschriftAktuelle Neurologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Alzheimer's Disease, Parkinson's Disease, and Huntington's Disease belong to the group of brain amyloid disorders and involve the formation and accumulation of misfolded disease-specific proteins. According to the amyloid cascade hypothesis, accumulation of the amyloid-beta peptide(A-beta) is central for the pathogenesis of Alzheimer's disease. Increasing evidence suggests that soluble precursor aggregates such as o…
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Zitierempfehlung
M Herbst, J Bieschke, Q Wang, R Lurz, A Boeddrich, A Otto, R Anwyl, DM Walsh, EE Wanker (2007) Induction of fibril-like beta-amyloid aggregates by a natural substance decreases soluble oligomers and protects from neurotoxicity. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2007-987948
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