CareLit · DOI-Nachweis · Aktuelle Neurologie
KLF-8: A novel integrin signalling molecule, which enhances malignant proliferation in gliomas and is expressed grade dependent
DOI 10.1055/s-2007-988039
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Romagna, N Thon, N Plesnila, S Grau, JC Tonn, R Goldbrunner, O Schnell
ZeitschriftAktuelle Neurologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objective: The downstream mechanisms used by integrins to promote proliferation of malignant cells in brain tumors are widely unknown. In the present study we investigate for the first time pivotal factors of a newly found integrin proliferation pathway including the potent transcription factor KLF-8 that stimulates cyclin D1 and subsequently G1/S-progression of the cell cycle in gliomas of different WHO grades. Met…
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Zitierempfehlung
A Romagna, N Thon, N Plesnila, S Grau, JC Tonn, R Goldbrunner, O Schnell (2007) KLF-8: A novel integrin signalling molecule, which enhances malignant proliferation in gliomas and is expressed grade dependent. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2007-988039
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