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Recombinant immunoblot for assessment of intrathecally synthesised paraneoplastic antineuronal antibodies in cerebrospinal fluid from patients with paraneoplastic neurological syndromes

O Stich, S Jarius, C Rasiah, R Voltz, S Rauer · Aktuelle Neurologie · Ausgabe 09/2007

DOI 10.1055/s-2007-988041

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Autor:innenO Stich, S Jarius, C Rasiah, R Voltz, S Rauer
ZeitschriftAktuelle Neurologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: Beside of pathophysiological interest, estimation of intrathecal synthesis (IS) of paraneoplastic antineuronal antibodies may increase the diagnostic sensitivity in rare cases of patients with clinically suggestive paraneoplastic neurological syndromes (PNS) and negative or uncertain results in serum. Detection of antigen-specific oligoclonal bands (OCB) in CSF seems to be the most sensitive marker of IS…

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O Stich, S Jarius, C Rasiah, R Voltz, S Rauer (2007) Recombinant immunoblot for assessment of intrathecally synthesised paraneoplastic antineuronal antibodies in cerebrospinal fluid from patients with paraneoplastic neurological syndromes. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2007-988041

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