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The hepatic cholesterol transporter gene ABCG8 confers increased gallstone risk in humans: combined affected sib pair and association study
DOI 10.1055/s-2007-988119
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Autor:innenF Grünhage, M Acalovschi, S Tirziu, M Walier, TF Wienker, A Ciocan, T Sauerbruch, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Genome-wide scans in inbred strains of mice have linked the genes encoding the hepatocanalicular cholesterol transporter ABCG5/G8 to gallstone formation. Five nonsynonymous coding single nucleotide polymorphisms (SNPs) in the orthologous human genes are associated with differences in serum cholesterol and plant sterol levels. We now tested these ABCG5/G8 SNPs for linkage and association with gallstone…
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Zitierempfehlung
F Grünhage, M Acalovschi, S Tirziu, M Walier, TF Wienker, A Ciocan, T Sauerbruch, F Lammert (2007) The hepatic cholesterol transporter gene ABCG8 confers increased gallstone risk in humans: combined affected sib pair and association study. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2007-988119
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