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Increased expression of the chemokine CXCL16 in intestinal inflammation and association of the CXCL16p.Ala181Val polymorphism with early disease onset and ileal involvement in patients with Crohn's disease

J Seiderer, J Dambacher, D Leistner, JH Niess, S Pfennig, J Diebold, D Haller, B Göke, T Ochsenkühn, P Lohse, HC Reinecker, S Brand · Zeitschrift für Gastroenterologie · Ausgabe 09/2007

DOI 10.1055/s-2007-988131

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Autor:innenJ Seiderer, J Dambacher, D Leistner, JH Niess, S Pfennig, J Diebold, D Haller, B Göke, T Ochsenkühn, P Lohse, HC Reinecker, S Brand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background/aim: We analyzed expression and signal transduction of the CXCL16-CXCR6 chemokine-ligand receptor system in intestinal inflammation and aimed to identify genetic determinants modulating its role in inflammatory bowel disease (IBD). Methods: CXCL16 and CXCR6 expression were analyzed by Northern blotting, PCR, Western blotting and immunohistochemistry in intestinal tissues including intestinal epithelial ce…

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J Seiderer, J Dambacher, D Leistner, JH Niess, S Pfennig, J Diebold, D Haller, B Göke, T Ochsenkühn, P Lohse, HC Reinecker, S Brand (2007) Increased expression of the chemokine CXCL16 in intestinal inflammation and association of the CXCL16p.Ala181Val polymorphism with early disease onset and ileal involvement in patients with Crohn's disease. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2007-988131

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