CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Cytotoxic T-lymphocyte antigen-4 haplotypes and T cell activation in irritable bowel syndrome
DOI 10.1055/s-2007-988138
Bibliografische Angaben
Nachweis in CareLit
Autor:innenT Liebregts, B Adam, C Bredack, S Lester, S Downie-Doyle, SM Brierley, M Gururatsakul, KR Pilkington, NJ Talley, G Holtmann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Immune activation may play a role in a subgroup of Irritable Bowel Syndrome (IBS). We have recently shown that PBMC- mediated cytokine secretion is significantly enhanced in IBS (Gastroenterology 2007; 132:913–920). This may reflect an impaired down-regulation of immune function. The cytotoxic T-lymphocyte antigen 4 (CTLA-4) is a negative signal for regulatory T-cell activation and the +49GA and the CT60A/G po…
Zitieren
Zitierempfehlung
T Liebregts, B Adam, C Bredack, S Lester, S Downie-Doyle, SM Brierley, M Gururatsakul, KR Pilkington, NJ Talley, G Holtmann (2007) Cytotoxic T-lymphocyte antigen-4 haplotypes and T cell activation in irritable bowel syndrome. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2007-988138
Mit CareLit weiterarbeiten