CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Vaccination with an ISCOM-based tumor vaccine and a TLR ligand overcomes tumor-induced immune suppression and leads to the eradication of established pancreatic carcinomas
DOI 10.1055/s-2007-988175
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Nachweis in CareLit
Autor:innenM Schnurr, C Jacobs, K Heckelsmiller, P Düwell, F Bauernfeind, C Bauer, M Dauer, S Endres, A Eigler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Pancreatic carcinoma is associated with a poor prognosis and new therapies are warranted. Tumor vaccination aims at inducing cytotoxic T cells capable of killing tumors. However, immune responses are severely impaired in cancer patients. Overcoming immune suppression is a challenge for new generation tumor vaccines. Methods: An ISCOM vaccine containing the model antigen OVA was generated. Mice were cha…
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Zitierempfehlung
M Schnurr, C Jacobs, K Heckelsmiller, P Düwell, F Bauernfeind, C Bauer, M Dauer, S Endres, A Eigler (2007) Vaccination with an ISCOM-based tumor vaccine and a TLR ligand overcomes tumor-induced immune suppression and leads to the eradication of established pancreatic carcinomas. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2007-988175
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