CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Characterization of candidate genes influencing migration, invasion and metastasis in genetically generated oral-esophageal cancer cells
DOI 10.1055/s-2007-988195
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Autor:innenS Hauß, H Kunert, C Franzke, EM Egenter, N Hirt, A Queisser, M Döbele, S Heeg, G Gössel, T Reinheckel, L Bruckner-Tudermann, C Peters, H Blum, O Opitz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: The ability of a tumor cell to migrate across the extracellular matrix (ECM) is a prerequisite for metastasis. In our cellular model of human oral-esophageal carcinogenesis we were able to recapitulate tumor development in a stepwise fashion. Cyclin D1 overexpression and p53 inactivation led to immortalization, additional EGFR overexpression induced an in vitro transformed phenotype, whereas additional…
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Zitierempfehlung
S Hauß, H Kunert, C Franzke, EM Egenter, N Hirt, A Queisser, M Döbele, S Heeg, G Gössel, T Reinheckel, L Bruckner-Tudermann, C Peters, H Blum, O Opitz (2007) Characterization of candidate genes influencing migration, invasion and metastasis in genetically generated oral-esophageal cancer cells. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2007-988195
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