CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The transcription factor interferon regulatory factor-4 controls experimental colitis via IL-6/sIL-6R
DOI 10.1055/s-2007-988357
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Autor:innenJ Mudter, L Amoussina, M Schenk, A Bruestle, B Weigmann, J Yu, S Wirtz, PR Galle, HA Lehr, S Rose-John, C Müller, M Lohoff, MF Neurath
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The interferon regulatory factor-4 (IRF4) is a central player in T cell regulation and differentiation. In the present study, we assessed the functional role of IRF4 in the immunopathogenesis of experimental colitis. As our previous data have shown, the number of IRF4 expressing mucosal T cells from IBD patients is increased compared with control patients. Consistently, adoptive transfer of wild-type but not IRF-4 d…
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Zitierempfehlung
J Mudter, L Amoussina, M Schenk, A Bruestle, B Weigmann, J Yu, S Wirtz, PR Galle, HA Lehr, S Rose-John, C Müller, M Lohoff, MF Neurath (2007) The transcription factor interferon regulatory factor-4 controls experimental colitis via IL-6/sIL-6R. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2007-988357
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