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Suppression of Hepatitis C Virus replication in vitro is mediated by TLR3- or TLR4-stimulated non-parenchymal liver cells

R Bröring, J Wu, Z Meng, P Hilgard, M Lu, M Trippler, G Gerken, J Schlaak · Zeitschrift für Gastroenterologie · Ausgabe 09/2007

DOI 10.1055/s-2007-988475

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Autor:innenR Bröring, J Wu, Z Meng, P Hilgard, M Lu, M Trippler, G Gerken, J Schlaak
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background & aims: Only little is known about the role of non-parenchymal liver cells (NPC) in the antiviral defense against HCV. Therefore, the aim of this study was to further elucidate the role of the IFN- and the Toll-like receptor (TLR) system in the control of HCV replication by NPC. Methods: Murine HCV replicon bearing MH1 cells were incubated with IFN-α, -β or -γ and TLR 1–9 ligands, respectively. In additio…

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R Bröring, J Wu, Z Meng, P Hilgard, M Lu, M Trippler, G Gerken, J Schlaak (2007) Suppression of Hepatitis C Virus replication in vitro is mediated by TLR3- or TLR4-stimulated non-parenchymal liver cells. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2007-988475

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