CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Deficiency of the potent calcification inhibitor fetuin-A promotes cholesterol crystallization in murine gallbladder bile in vivo
DOI 10.1055/s-2007-988483
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Autor:innenS Hillebrandt, C Schäfer, W Jahnen-Dechent, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Most gallstones have a pigment-rich, calcium salt nidus, consistent with calcium precipitation favoring heterogeneous nucleation of cholesterol crystals in bile. Recently we have shown that serum protein alpha2-Heremans-Schmid glycoprotein (AHSG, a.k.a. fetuin-A) is a systemically acting potent inhibitor of ectopic calcification (Schäfer et al. J Clin Invest 2003;112:357–66). Since fetuin-A is also present in bile,…
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Zitierempfehlung
S Hillebrandt, C Schäfer, W Jahnen-Dechent, F Lammert (2007) Deficiency of the potent calcification inhibitor fetuin-A promotes cholesterol crystallization in murine gallbladder bile in vivo. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2007-988483
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