CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Transgenic overexpression of Abcb11 enhances biliary bile salt outputs but does not affect cholesterol cholelithogenesis in mice
DOI 10.1055/s-2007-988484
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Nachweis in CareLit
Autor:innenD Wang, A Schmitz, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Cholesterol gallstone disease is a complex genetic trait and induced by multiple but as yet unknown genes. A major Lith gene, Lith1 was first identified on chromosome 2 in gallstone-susceptible C57L mice compared with resistant AKR mice. Abcb11 encoding the canalicular bile salt export pump in the hepatocyte, is co-located within the Lith1 QTL region and its hepatic expression is significantly higher in C57L mice th…
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Zitierempfehlung
D Wang, A Schmitz, F Lammert (2007) Transgenic overexpression of Abcb11 enhances biliary bile salt outputs but does not affect cholesterol cholelithogenesis in mice. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2007-988484
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