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Nitric oxide is a mediator of the adenosine-induced vasodilatation of the hepatic artery in CCl4-cirrhotic rats

A Zipprich, C Ripoll, MR Loureiro-Silva, RJ Groszmann · Zeitschrift für Gastroenterologie · Ausgabe 09/2007

DOI 10.1055/s-2007-988517

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Autor:innenA Zipprich, C Ripoll, MR Loureiro-Silva, RJ Groszmann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben

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Background and aim: In normal livers, hepatic arterial vasodilatation produced by adenosine is mediated by the adenosine receptor A2a and this response is nitric oxide independent. It has been shown that muscle hypoxia leads to an increase in tissue adenosine and vasodilatation. This effect is modulated by the A1 receptor and mediated by nitric oxide. Additionally, we have previously reported that hepatic arterial v…

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A Zipprich, C Ripoll, MR Loureiro-Silva, RJ Groszmann (2007) Nitric oxide is a mediator of the adenosine-induced vasodilatation of the hepatic artery in CCl4-cirrhotic rats. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2007-988517

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