CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Gene polymorphisms in the secretory signal peptide of TGF-β1 affect the cellular synthesis, secretion and processing of TGF-β1 and secretion is modulated by the latent TGF-β binding protein-1 (LTBP-1) and furin protease
DOI 10.1055/s-2007-988523
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Autor:innenS Mohren, WN Vreden, AM Gressner, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: We have demonstrated that gene polymorphisms in the coding region of TGF-β1 contribute to the outcome of fibrogenesis in patients suffering from Hepatitis C infection [1, 2]. In addition, the polymorphism at codon 25 from arginine to proline was previously shown to be associated with interindividual variation in levels of TGF-β1 production [3]. Aims: In this study, we analyzed the impact of gene polymorphisms…
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Zitierempfehlung
S Mohren, WN Vreden, AM Gressner, R Weiskirchen (2007) Gene polymorphisms in the secretory signal peptide of TGF-β1 affect the cellular synthesis, secretion and processing of TGF-β1 and secretion is modulated by the latent TGF-β binding protein-1 (LTBP-1) and furin protease. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2007-988523
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