CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Obstructive cholestasis down-regulates Oatp1 by TNFα signalling without affecting Oatp2 and Oatp4 expression and Sodium-independent bile salt uptake in rat liver
DOI 10.1055/s-2007-988537
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Geier, CG Dietrich, M Trauner, C Gartung
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2007
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background & Aims: Hepatic uptake of bile salts is mediated by sodium-dependent and sodium-independent transport systems. During extrahepatic cholestasis both function and expression of the Na+/taurocholate cotransporting polypeptide (Ntcp) are down-regulated. To test whether hepatic sodium-independent organic anion transporting polypeptides (Oatp1/Oatp1a1, Oatp2/Oatp1a4, Oatp4/Oatp1b2) are also affected by extrahep…
Zitieren
Zitierempfehlung
A Geier, CG Dietrich, M Trauner, C Gartung (2007) Obstructive cholestasis down-regulates Oatp1 by TNFα signalling without affecting Oatp2 and Oatp4 expression and Sodium-independent bile salt uptake in rat liver. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-2007-988537
Mit CareLit weiterarbeiten