CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Cox–2 contributes to the selective induction of cell death by the endocannabinoid 2-arachidonoyl glycerol in hepatic stellate cells through generation of prostaglandin-gycerol esters
DOI 10.1055/s-2008-1037457
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Autor:innenSV Siegmund, A Wojtalla, F Herweck, MV Singer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: We have shown previously that the endogenous cannabinoid 2-arachidonoyl glycerol (2-AG) is a lipid mediator that blocks proliferation and induces apoptosis in hepatic stellate cells (HSCs), but not in hepatocytes. However, the exact molecular mechanisms of this selective induction of HSC death still need to be clarified. AIM: To analyze a possible role of COX–2 in the differential cell death of primary HSCs an…
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Zitierempfehlung
SV Siegmund, A Wojtalla, F Herweck, MV Singer (2008) Cox–2 contributes to the selective induction of cell death by the endocannabinoid 2-arachidonoyl glycerol in hepatic stellate cells through generation of prostaglandin-gycerol esters. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037457
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