CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Transcriptional Targeting of Activated Hepatic Stellate Cells by Modular Promoter Fragments
DOI 10.1055/s-2008-1037462
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Autor:innenM Friedrich, AM Gressner, R Weiskirchen, J Herrmann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Transdifferentiation of hepatic stellate cells (HSC) into myofibroblast-like cells is a key event in liver fibrogenesis accompanied by differential gene regulation. Antifibrotic strategies focus on manipulation of this relevant cell type, e.g. induction of HSC apoptosis, but to date a specific and easy-to-handle targeting of activated HSC is not reported. As demonstrated by Lemken et al. [1] a targeting of reporter…
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Zitierempfehlung
M Friedrich, AM Gressner, R Weiskirchen, J Herrmann (2008) Transcriptional Targeting of Activated Hepatic Stellate Cells by Modular Promoter Fragments. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037462
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