CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Synergistic effects of Platelet-derived growth factor-BB and Transforming growth factor-β1 on profibrogenic activities in hepatic stellate cells
DOI 10.1055/s-2008-1037465
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Autor:innenO Scherner, SK Meurer, E Borkham-Kamphorst, S Sauer-Lehnen, WN Vreden, AM Gressner, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background/Aims: Platelet-derived growth factor (PDGF)-BB and transforming growth factor (TGF)-β1 are important profibrogenic cytokines involved in liver fibrogenesis. They trigger the activation of hepatic stellate cells (HSC) and the synthesis of extracellular matrix (ECM) components, respectively. The pivotal role of both cytokines has been figured out by using antagonistic strategies [1]. It has been previously…
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Zitierempfehlung
O Scherner, SK Meurer, E Borkham-Kamphorst, S Sauer-Lehnen, WN Vreden, AM Gressner, R Weiskirchen (2008) Synergistic effects of Platelet-derived growth factor-BB and Transforming growth factor-β1 on profibrogenic activities in hepatic stellate cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037465
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