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TGF-beta induces IL–15 in hepatocytes: A potential new role for IL–15 in liver disease

P Godoy, E Bulanova, HL Weng, A Bachmann, E Üeberham, S Bulfone-Paus, S Dooley · Zeitschrift für Gastroenterologie · Ausgabe 01/2008

DOI 10.1055/s-2008-1037468

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Autor:innenP Godoy, E Bulanova, HL Weng, A Bachmann, E Üeberham, S Bulfone-Paus, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Liver fibrogenesis is a process involving a complex interaction of cellular components. We recently described a new role for hepatocytes in the process of fibrogenesis, in which TGF-β induces expression and secretion of CTGF, another potent profibrogenic cytokine. Interleukin–15 has emerged as a new player in several models of liver damage, but its precise role has not yet been determined. Real Time PCR showed that…

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Zitierempfehlung

P Godoy, E Bulanova, HL Weng, A Bachmann, E Üeberham, S Bulfone-Paus, S Dooley (2008) TGF-beta induces IL–15 in hepatocytes: A potential new role for IL–15 in liver disease. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037468

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