CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
TGF-β and hepatocyte transdifferentiation in liver fibrogenesis
DOI 10.1055/s-2008-1037471
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Dooley, J Hamzavi, L Ciuclan, P Godoy, I Ilkavets, S Ehnert, E Ueberham, R Gebhardt, R Gebhardt, S Kanzler, A Geier, K Breitkopf, HL Weng, PR Mertens
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Dysregulated cytokine metabolism is a common feature of alcoholic liver disease and especially signaling of TGF-β is critical for progression of steatohepatitis to fibrosis. The profibrogenic role that TGF-β exerts in the liver has mostly been attributed to hepatic stellate cell activation and excess matrix synthesis. Hepatocytes are also highly responsive to TGF-β with increased apoptosis rates. However, in primary…
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Zitierempfehlung
S Dooley, J Hamzavi, L Ciuclan, P Godoy, I Ilkavets, S Ehnert, E Ueberham, R Gebhardt, R Gebhardt, S Kanzler, A Geier, K Breitkopf, HL Weng, PR Mertens (2008) TGF-β and hepatocyte transdifferentiation in liver fibrogenesis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037471
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