CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
JNK dependent regulation of TGF-β target genes in hepatic stellate cells
DOI 10.1055/s-2008-1037474
Bibliografische Angaben
Nachweis in CareLit
Autor:innenL Wickert, K Kruschinsky, J Herrmann, A Gressner
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Hepatic fibrosis is a wound healing process characterized by accumulation of several extracellular matrix proteins e.g. collagen1, which is initiated amongst others by activating hepatic stellate cells (HSC) through transforming growth factor β (TGF-β). TGF-β binds and phosphorylates transmembrane receptors, which in turn propagate the signal via Smads into the nucleus in order to regulate gene expression. The conne…
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Zitierempfehlung
L Wickert, K Kruschinsky, J Herrmann, A Gressner (2008) JNK dependent regulation of TGF-β target genes in hepatic stellate cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037474
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