CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The selective induction of apoptosis in HSC by the targeted thymidine kinase/Ganciclovir system
DOI 10.1055/s-2008-1037480
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Autor:innenE Kovalenko, E Borkham-Kamphorst, M Bomble, AM Gressner, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background/Aims: Liver fibrogenesis is the consequence of a dysbalance of synthesis and degradation of extracellular matrix components. During hepatic fibrogenesis, hepatic stellate cells (HSC) are the major producer of these constituents. Therefore, HSC are in the focus of antifibrotic therapies. A previous report from us have demonstrated that the thymidine kinase/Ganciclovir system directed under transcriptional…
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Zitierempfehlung
E Kovalenko, E Borkham-Kamphorst, M Bomble, AM Gressner, R Weiskirchen (2008) The selective induction of apoptosis in HSC by the targeted thymidine kinase/Ganciclovir system. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037480
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