CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
BETA-ADRENERGIC BLOCKADE OF THE SYMPATHETIC NERVOUS SYSTEM DECELERATES PERIPORTAL FIBROSIS IN ABCB4 KNOCKOUT MICE
DOI 10.1055/s-2008-1037489
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Autor:innenI Strack, M Scheffler, E Konze, K Wendland, H Varnholt, S Schulte, HP Dienes, M Odenthal
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
BACKGROUND AND AIM: Hepatic Stellate Cells (HSC) express α- and β-adrenoceptors and adrenergic inhibition results in reduced collagen I and α-smooth muscle actin (SMA) expression. Therefore, HSC were suggested to be the main cellular targets of sympathetic inhibition by β-blockers in experimental sinusoidal fibrosis. In order to study the role of the sympathetic nervous system in liver fibrogenesis we used the Abcb4…
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Zitierempfehlung
I Strack, M Scheffler, E Konze, K Wendland, H Varnholt, S Schulte, HP Dienes, M Odenthal (2008) BETA-ADRENERGIC BLOCKADE OF THE SYMPATHETIC NERVOUS SYSTEM DECELERATES PERIPORTAL FIBROSIS IN ABCB4 KNOCKOUT MICE. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037489
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