CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
IKK2 hepatocyte specific deletion accelerates the liver regeneration and enhances the innate immune response in mice
DOI 10.1055/s-2008-1037497
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Nachweis in CareLit
Autor:innenY Malato, N Beraza, LE Sander, L Sander, M Al-Masaoudi, M Pasparakis, C Trautwein
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
After injury, the liver has the ability to restore its mass and function through a process called “liver regeneration“. In resting cells, NF-κB is confined inactive in the cytoplasm, bound to its inhibitor IκB. After stimulation, IκB is phosphorylated by the IKK complex (composed of two catalytic subunits IKK1 and IKK2 and a regulatory subunit NEMO) leading IκB to a proteasomal degradation and thus liberating NF-κB…
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Zitierempfehlung
Y Malato, N Beraza, LE Sander, L Sander, M Al-Masaoudi, M Pasparakis, C Trautwein (2008) IKK2 hepatocyte specific deletion accelerates the liver regeneration and enhances the innate immune response in mice. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037497
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