CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
PDGF isoform expression in carbon tetrachloride induced chronic liver injury
DOI 10.1055/s-2008-1037502
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Autor:innenE Borkham-Kamphorst, E Kovalenko, M Bomble, AM Gressner, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Platelet-derived growth factor (PDGF) plays an important role in liver fibrogenesis, whereby PDGF-B and –D act as potent mitogens in culture-activated hepatic stellate cells (HSC) (1, 2). Induction of PDGFR-beta in HSC has been well documented in single dose CCL4 induced acute liver injury and in early bile duct ligated models in vivo (3). Of the newly discovered Isoforms PDGF-C and -D, only PDGF-D shows signi…
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Zitierempfehlung
E Borkham-Kamphorst, E Kovalenko, M Bomble, AM Gressner, R Weiskirchen (2008) PDGF isoform expression in carbon tetrachloride induced chronic liver injury. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037502
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