CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The CC chemokine RANTES (CCL5) mediates liver fibrosis in mice and humans
DOI 10.1055/s-2008-1037506
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Autor:innenML Berres, A Rüland, M Moreno Zaldivar, D Scholten, N Gaßler, C Weber, C Trautwein, HE Wasmuth
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Chemokines are inflammatory mediators during acute and chronic liver injury. The chemokine RANTES (CCL5) directs lymphocytes to inflamed tissues and directly activates hepatic stellate cells in vitro through interaction with CCR5. These functions define RANTES as an interesting target for antifibrotic therapies. We here present data defining the role of RANTES in human and murine liver fibrosis. Methods: In hu…
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Zitierempfehlung
ML Berres, A Rüland, M Moreno Zaldivar, D Scholten, N Gaßler, C Weber, C Trautwein, HE Wasmuth (2008) The CC chemokine RANTES (CCL5) mediates liver fibrosis in mice and humans. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037506
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