CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Generation of the conditionally replicating adenovirus Adsensor-p53T for the treatment of tumors with harboring activated hTERT and aberrations in p53-transcriptional activity
DOI 10.1055/s-2008-1037516
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Nachweis in CareLit
Autor:innenE Gürlevik, TC Wirth, K Freimann, MP Manns, S Kubicka, F Kühnel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Oncolytic virotherapy is a novel and challenging approach for the treatment of solid tumors. Major challenges in virotherapy are tight restriction of viral replication to malignant cells combined with a large spectrum of potential target tumors. Aim of the study was the generation of a conditionally replicating adenovirus able to recognize both activated hTert and an aberrant transcriptional p53-status in target cel…
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Zitierempfehlung
E Gürlevik, TC Wirth, K Freimann, MP Manns, S Kubicka, F Kühnel (2008) Generation of the conditionally replicating adenovirus Adsensor-p53T for the treatment of tumors with harboring activated hTERT and aberrations in p53-transcriptional activity. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037516
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