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Growth Stimulation and Anti-apoptotic Properties of a Novel Ursodeoxycholic Lysophosphatidylethanolamide in HepG2 cells: Implications for Treatment of Liver Diseases

W Chamulitrat, J Burhenne, T Rehlen, W Stremmel · Zeitschrift für Gastroenterologie · Ausgabe 01/2008

DOI 10.1055/s-2008-1037540

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Autor:innenW Chamulitrat, J Burhenne, T Rehlen, W Stremmel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Homeostasis of phospholipids is altered during pathogenesis of liver diseases including alcohol and non-alcoholic steatohepatitis (NASH). There is no generally accepted drug therapy to treat these diseases. Hepatic phosphatidylcholine (PC) is often depleted. As a therapy strategy, we synthesized a bile acid-phospholipid conjugate which targets hepatocytes via the bile acid transport system. We performed amide coupli…

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Zitierempfehlung

W Chamulitrat, J Burhenne, T Rehlen, W Stremmel (2008) Growth Stimulation and Anti-apoptotic Properties of a Novel Ursodeoxycholic Lysophosphatidylethanolamide in HepG2 cells: Implications for Treatment of Liver Diseases. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037540

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