CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The Oncolytic Adenovirus Adp53-sensor Replicates Selectively in p53-altered Tumor Cells and Potential Tumor Spectrum is not Limited by the p73 Status
DOI 10.1055/s-2008-1037556
Bibliografische Angaben
Nachweis in CareLit
Autor:innenF Kühnel, TC Wirth, L Zender, E Gürlevik, MP Manns, S Kubicka
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Oncolytic virotherapy provides a promising and novel mean for the treatment of solid tumors. Major challenges in virotherapy are tight restriction of viral replication to malignant cells and a broad range of potential target tumors. The aim of the study was the establishment of a conditionally replicating adenovirus able to recognize the transcriptional p53-status of target cell and able to consequently respond by t…
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Zitierempfehlung
F Kühnel, TC Wirth, L Zender, E Gürlevik, MP Manns, S Kubicka (2008) The Oncolytic Adenovirus Adp53-sensor Replicates Selectively in p53-altered Tumor Cells and Potential Tumor Spectrum is not Limited by the p73 Status. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037556
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