CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Translocation of the Wilson disease protein ATP7B is independent of Murr1/ COMMD1 and Rab7
DOI 10.1055/s-2008-1037564
Bibliografische Angaben
Nachweis in CareLit
Autor:innenKH Weiss, JC Lozoya, S Tuma, D Gotthardt, J Reichert, R Ehehalt, W Stremmel, J Füllekrug
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Wilson disease is a genetic disorder of copper metabolism. Impaired biliary excretion results in a gradual accumulation of copper predominantely in liver and brain, leading to severe neurological symptoms and liver damage. The gene defect lies in the Wilson disease protein ATP7B, a copper transporting ATPase highly active in hepatocytes. The two major functions of ATP7B in the liver are the copper loading of cerulop…
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Zitierempfehlung
KH Weiss, JC Lozoya, S Tuma, D Gotthardt, J Reichert, R Ehehalt, W Stremmel, J Füllekrug (2008) Translocation of the Wilson disease protein ATP7B is independent of Murr1/ COMMD1 and Rab7. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037564
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