CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
DOTAP VEGF-A siRNA containing an immunostimulatory motif significantly increased anti tumoral therapy efficacy in an HCC orthotopic fibrotic tumor model
DOI 10.1055/s-2008-1037569
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Kornek, V Lukacs-Kornek, E Raskopf, U Becker, M Klöckner, T Sauerbruch, V Schmitz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
BACKGROUND/AIMS Most experimental therapy studies are performed in mice that bear subcutaneous or orthotopic hepatoma but are otherwise healthy and non-fibrotic. However, the majority of hepatocellular carcinoma develops in patients suffering from pre-existing liver fibrosis. Here we investigated the efficacy of a standard experimental therapeutic approach to interrupt the VEGF/VEGFR cascade via VEGF-A silencing in…
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Zitierempfehlung
M Kornek, V Lukacs-Kornek, E Raskopf, U Becker, M Klöckner, T Sauerbruch, V Schmitz (2008) DOTAP VEGF-A siRNA containing an immunostimulatory motif significantly increased anti tumoral therapy efficacy in an HCC orthotopic fibrotic tumor model. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037569
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