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Inhibition of the growth suppressor gene Necdin results in increased proliferation of primary murine hepatocytes

U Rüdrich · Zeitschrift für Gastroenterologie · Ausgabe 01/2008

DOI 10.1055/s-2008-1037588

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Autor:innenU Rüdrich
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

With microarrays we identified a subset of 44 genes, which were up-regulated in the early mouse fetal vs. adult liver. One of the genes, Necdin, which is described as a cell growth suppressor in postmitotic neurons, was analysed. To study the physiological regulation of Necdin during adult liver regeneration we performed 2/3 hepatectomy and analysed expression at various time points (0–48h). Necdin expression relati…

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Zitierempfehlung

U Rüdrich (2008) Inhibition of the growth suppressor gene Necdin results in increased proliferation of primary murine hepatocytes. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037588

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