CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
PD1 regulates alloreactive donor T cells after liver transplantation in graft-versus-host-disease
DOI 10.1055/s-2008-1037589
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Autor:innenM Schuchmann, RG Meyer, S Gregor, E Distler, K Bender, E von Stebuth, C Huber, PR Galle, G Otto, W Herr
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction Graft versus host disease (GVHD) after liver transplantation (LTx) is a rare complication yet associated with a high mortality. Donor T cells, sited in high numbers in the liver graft are mediators of allo-reactivity. Recent studies suggest that allo-reactive T cells are regulated by CD4/CD25/FoxP3-positive regulatory T cells (Tregs). Here, we provide evidence of an alternative regulatory pathway involv…
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Zitierempfehlung
M Schuchmann, RG Meyer, S Gregor, E Distler, K Bender, E von Stebuth, C Huber, PR Galle, G Otto, W Herr (2008) PD1 regulates alloreactive donor T cells after liver transplantation in graft-versus-host-disease. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037589
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