CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Telomere shortening is a prognostic factor in chronic hepatitis C virus infection
DOI 10.1055/s-2008-1037610
Bibliografische Angaben
Nachweis in CareLit
Autor:innenH Jiang, K Deterding, Z Ju, A Lechel, HL Tillmann, M Krüger, MP Manns, H Wedemeyer, LK Rudolph
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2008
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background & Aims: Telomere shortening limits the proliferative capacity of human cells to 50–70 cell divisions. In humans, telomere shortening occurs in most organs during aging and characterizes the end stage of chronic diseases, such as cirrhosis. A current concept indicates that dysfunctional telomeres limit the regenerative capacity of cells and organs by inducing DNA damage signals leading to cell cycle arrest…
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Zitierempfehlung
H Jiang, K Deterding, Z Ju, A Lechel, HL Tillmann, M Krüger, MP Manns, H Wedemeyer, LK Rudolph (2008) Telomere shortening is a prognostic factor in chronic hepatitis C virus infection. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2008-1037610
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